5-HT1D Receptors Regulate 5-HT Release in the Rat Raphe Nuclei In Vivo Voltammetry and In Vitro Superfusion Studies
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چکیده
منابع مشابه
Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro.
The "club drug" 3,4-methylenedioxymethamphetamine (MDMA; also known as ecstasy) binds preferentially to and reverses the activity of the serotonin transporter, causing release of serotonin [5-hydroxytryptamine (5-HT)] stores from nerve terminals. Subsequent activation of postsynaptic 5-HT receptors by released 5-HT has been shown to be critical for the unique psychostimulatory effects of MDMA. ...
متن کاملRelationship between neonatal testosterone and 5-hydroxytryptamine (5 HT) in controlling the pattern of LH release in adult rats
Relationship between neonatal testosterone and 5-hydroxytryptamine (5-HT) in controlling the pattern of LH release in adult rats was investigated in this study. Hypothalamic 5-HT concentrations are transiently lower in male as compared to female Wistar rats in the second week post-partum (pp). It has also been shown that pharmacologically potentiating 5-HT activity during this period feminizes ...
متن کاملRelationship between neonatal testosterone and 5-hydroxytryptamine (5 HT) in controlling the pattern of LH release in adult rats
Relationship between neonatal testosterone and 5-hydroxytryptamine (5-HT) in controlling the pattern of LH release in adult rats was investigated in this study. Hypothalamic 5-HT concentrations are transiently lower in male as compared to female Wistar rats in the second week post-partum (pp). It has also been shown that pharmacologically potentiating 5-HT activity during this period feminizes ...
متن کاملPharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons
G protein-activated inwardly rectifying potassium (GIRK) channels in 5-HT neurons are assumed to be principal effectors of 5-hydroxytryptamine 1A (5-HT1A) autoreceptors, but their pharmacology, subunit composition and the role in regulation of 5-HT neuron activity have not been fully elucidated. We sought for a pharmacological tool for assessing the functional role of GIRK channels in 5-HT neur...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 1995
ISSN: 0893-133X
DOI: 10.1016/0893-133x(95)00109-q